Glomerulonephritis affecting most of the renal glomeruli; it may lead to azotemia. ... (05 Mar 2000) ... 
a severe form of glomerulonephritis with proliferative changes in more than half the glomeruli, frequently with epithelial crescent formation and necrosis; it is often seen in cases of advanced systemic lupus erythematosus.
Type: Term Definitions: 1. glomerulonephritis affecting most of the renal glomeruli; it may lead to azotemia.